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A paper submitted by Pauling to the Proceedings of the National Academy of Sciences and accepted for publication on June 11, 1991 was later revoked by the editor under questionable circumstances: "We are aware that this pullback was not the decision of an individual. It happened in the interest of those who are personally or economically dependent on the present dogma of human cardiovascular disease."In the mid-1930s, Pauling shifted his interest towards biological molecules and protein structures, although it was his work on vitamin C which generated much controversy. Pauling popularised vitamin C as an effective therapy for terminal cancer patients and the common cold. However, the failure of randomised trials by the Mayo Clinic to demonstrate any benefit and the public debate that ensued resulted in the medical establishment eventually rejecting his claims as quackery.
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