LAURA KNIGHT-JADCZYK AND JOE QUINN
Since the 9/11 attacks, no book has provided a satisfactory answer as to WHY the attacks occurred and who was ultimately responsible for carrying them out - until now.
The mouse genome was sequenced in 2002 as a primary model in which to study gene function and human diseases and to develop drugs. This was followed by maps of transcribed messenger RNA molecules and of long, non-protein-coding RNAs, which facilitated such experiments and analysis. Yet although 17 mouse strains have been sequenced, genome function and regulation cannot be understood by sequence analysis alone. Now, in four papers published in this issue, the Mouse ENCODE Consortium presents data sets that dramatically enhance our understanding of the regulation of the mouse genome, and of the similarities and differences compared with the human genome. (Emphasis added.)The four papers in Nature announce the findings from the Mouse ENCODE Consortium: