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Yoshiki Sasai, study leader from the RIKEN Centre for Developmental Biology in Kobe, Japan, and a team of researchers, have used embryonic stem cells from mice to create a rudimentary eye, which could eventually allow scientists to treat blindness and other eye-related problems.
Other researchers in the past have participated in similar research, but were not able to create a complex organ such as the eye from a group of cells. For instance, Professor Robin Ali, a molecular geneticist at the UCL Institute of Ophthalmology in London, successfully transplanted light-sensitive cells from newborn mice to the retinas of adult mice. Ali is still unsure as to whether the vision of the adult mice has improved.
Now, Sasai has grown an eye by using an optic cup, which is a structure that holds light-sensitive cells and neurons required to see properly. The optic cup is responsible for forming the retina. The team then cultured a floating cluster of embryonic stem cells, and the cells required to make the eye took shape on their own. The result was a 2mm diameter eye, which is the size of an eye of an infant mouse.
